| 16/10/2021 |  |
1 | x | 0 | LilleLille |  |
|||
| 16/10/2021 |  |
LyonLyon | 2 | x | 0 | AS MonacoAS Monaco |  |
||
| 17/10/2021 | |
1 | x | 0 | NiceNice |  |
|||
| 17/10/2021 |  |
BordeauxBordeaux | 1 | x | 1 | NantesNantes |  |
||
| 17/10/2021 |  |
BrestBrest | 1 | x | 1 | Stade de ReimsReims |  |
||
| 17/10/2021 |  |
MetzMetz | 0 | x | 3 | Stade RennaisStade Rennais |  |
||
| 17/10/2021 |  |
StrasbourgStrasbourg | 5 | x | 1 | Saint-ÉtienneSaint-Étienne |  |
||
| 17/10/2021 |  |
MontpellierMontpellier | 1 | x | 0 | LensLens |  |
||
| 17/10/2021 |  |
MarseilleMarseille | 4 | x | 1 | LorientLorient |  |