| 26/11/2021 |  |
VfB StuttgartStuttgart | 2 | x | 1 | MainzMainz |  |
||
| 27/11/2021 |  |
FC KölnKöln | 4 | x | 1 | Borussia MönchengladbachGladbach |  |
||
| 27/11/2021 |  |
Hertha BerlinHertha | 1 | x | 1 | FC AugsburgAugsburg |  |
||
| 27/11/2021 |  |
VfL WolfsburgWolfsburg | 1 | x | 3 | Borussia DortmundDortmund |  |
||
| 27/11/2021 |  |
Bayern MünchenBayern | 1 | x | 0 | Arminia BielefeldArminia Bielefeld |  |
||
| 28/11/2021 |  |
Eintracht FrankfurtFrankfurt | 2 | x | 1 | Union BerlinUnion Berlin |  |
||
| 28/11/2021 |  |
RB LeipzigLeipzig | 1 | x | 3 | Bayer LeverkusenBayer Leverkusen |  |