| 07/05/2022 |  |
FC KölnKöln | 0 | x | 1 | VfL WolfsburgWolfsburg |  |
||
| 07/05/2022 |  |
SC FreiburgFreiburg | 1 | x | 4 | Union BerlinUnion Berlin |  |
||
| 07/05/2022 |  |
TSG HoffenheimHoffenheim | 2 | x | 4 | Bayer LeverkusenBayer Leverkusen |  |
||
| 07/05/2022 |  |
Hertha BerlinHertha | 1 | x | 2 | MainzMainz |  |
||
| 08/05/2022 |  |
Eintracht FrankfurtFrankfurt | 1 | x | 1 | Borussia MönchengladbachGladbach |  |
||
| 08/05/2022 |  |
Bayern MünchenBayern | 2 | x | 2 | VfB StuttgartStuttgart |  |
||
| 08/05/2022 |  |
RB LeipzigLeipzig | 4 | x | 0 | FC AugsburgAugsburg |  |