| 07/11/2021 |  |
Stade de ReimsReims | 0 | x | 0 | AS MonacoAS Monaco |  |
||
| 07/11/2021 |  |
Saint-ÉtienneSaint-Étienne | 3 | x | 2 |  |
|||
| 07/11/2021 |  |
NiceNice | 0 | x | 1 | MontpellierMontpellier |  |
||
| 07/11/2021 |  |
Stade RennaisStade Rennais | 4 | x | 1 | LyonLyon |  |
||
| 19/11/2021 | |
AS MonacoAS Monaco | 2 | x | 2 | LilleLille |  |
||
| 20/11/2021 |  |
Paris Saint-GermainPSG | 3 | x | 1 | NantesNantes |  |
||
| 20/11/2021 | |
Stade RennaisStade Rennais | 2 | x | 0 | MontpellierMontpellier | |
||
| 21/11/2021 |  |
BrestBrest | 4 | x | 0 | LensLens |  |
||
| 21/11/2021 |  |
AngersAngers | 1 | x | 0 | LorientLorient |  |