| 23/10/2021 |  |
2 | x | 1 | VillarrealVillarreal |  |
|||
| 24/10/2021 |  |
SevillaSevilla | 5 | x | 3 | LevanteLevante |  |
||
| 24/10/2021 |  |
BarcelonaBarcelona | 1 | x | 2 | Real MadridReal Madrid |  |
||
| 24/10/2021 |  |
Real BetisReal Betis | 3 | x | 2 | |
|||
| 24/10/2021 |  |
Atlético MadridAtlético Madrid | 2 | x | 2 | Real SociedadReal Sociedad |  |
||
| 25/10/2021 |  |
GetafeGetafe | 0 | x | 3 | Celta VigoCelta Vigo |  |
||
| 26/10/2021 |  |
AlavésAlavés | 1 | x | 0 | ElcheElche |  |
||
| 26/10/2021 | |
VillarrealVillarreal | 3 | x | 3 | CádizCádiz |  |
||
| 26/10/2021 |  |
EspanyolEspanyol | 1 | x | 1 | |
|||
| 27/10/2021 |  |
MallorcaMallorca | 1 | x | 1 | SevillaSevilla | |